Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10919806 | Radiotherapy and Oncology | 2011 | 6 Pages |
Abstract
Our data suggest that melanomas are not uniformly radioresistant with a significant subset displaying inherent radiosensitivity. Pharmacologic inhibition of B-RAF with PLX-4032 effectively radiosensitized B-Raf+ melanoma cells suggesting that this combination approach could provide improved radiotherapeutic response in B-Raf+ melanoma patients.
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Authors
Maria J. Sambade, Eldon C. Peters, Nancy E. Thomas, William K. Kaufmann, Randall J. Kimple, Janiel M. Shields,