Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10920159 | Radiotherapy and Oncology | 2005 | 9 Pages |
Abstract
Hypoxia can down-regulate expression of DNA-dsb repair genes in both normal and cancer cells. If associated with a functional decrease in DNA-dsb repair, this observation could provide a potential basis for the observed genetic instability within tumor cells exposed to hypoxia.
Related Topics
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Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
Alice X. Meng, Farid Jalali, Andrew Cuddihy, Norman Chan, Ranjit S. Bindra, Peter M. Glazer, Robert G. Bristow,