Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10924293 | Seminars in Oncology | 2016 | 57 Pages |
Abstract
Various clinical and epidemiologic studies show that nonsteroidal anti-inflammatory drugs (NSAIDs), including aspirin and cyclooxygenase inhibitors (COXIBs) help prevent cancer. Since eicosanoid metabolism is the main inhibitory targets of these drugs the resulting molecular and biological impact is generally accepted. As our knowledge base and technology progress we are learning that additional targets may be involved. This review attempts to summarize these new developments in the field.
Keywords
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Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
Asad Umar, Vernon E. Steele, David G. Menter, Ernest T. Hawk,