Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10926186 | Cell Calcium | 2015 | 11 Pages |
Abstract
- Paramecium cells possess a regular, epigenetically controlled arrangement of sites with molecules involved in Ca2+ signalling.
- Ca2+-release channels (CRCs) identical with, or similar to InsP3- and ryanodine-receptors occur in trafficking membranes.
- Among them are true InsP3 receptors in the contractile vacuole complex for constitutive Ca2+ reflux after sequestration.
- Ryanodine-receptor-like CRCs localised to cortical stores (alveoli) are activated by RyR activators for trichocyst exocytosis.
- Immuno-localisation in the light and electron microscope correlates with the defects detected after gene silencing.
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Authors
Helmut Plattner,