| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10926199 | Cell Calcium | 2015 | 8 Pages |
Abstract
- Ca2+ chelator EGTA increases the permeability of smooth muscle cells for Na+ and K+.
- Exposure to EGTA results in â¼5-fold elevation of the intracellular [Na+]/[K+] ratio.
- Na+,K+-ATPase inhibition and Ca2+-depletion lead to similar transcriptomic changes.
- Increased [Na+]i/[K+]i contributes to transcriptomic changes in Ca2+-depleted cells.
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![Transcriptomic changes in Ca2+-depleted cells: Role of elevated intracellular [Na+]/[K+] ratio](/preview/png/10926199.png "First Page Preview: Transcriptomic changes in Ca2+-depleted cells: Role of elevated intracellular [Na+]/[K+] ratio")
Authors
Svetlana V. Koltsova, Johanne Tremblay, Pavel Hamet, Sergei N. Orlov,