Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10926204 | Cell Calcium | 2015 | 9 Pages |
Abstract
- p11 (S100A10) modulates calcium signaling in healthy cardiomyocytes.
- p11 induction positively modulates the cardiac 5-HT4R pathway.
- Cardiomyocyte p11 expression is induced by BDNF or imipramine.
- Activation of the cardiac 5-HT4R pathway is associated with diastolic Ca2+ waves.
- We highlighted a potential explanation for antidepressant cardiotoxicity.
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Authors
Pierre Meschin, Marie Demion, Olivier Cazorla, Amanda Finan, Jérôme Thireau, Sylvain Richard, Alain Lacampagne,