| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10926207 | Cell Calcium | 2015 | 34 Pages |
Abstract
- The effects of PKC inhibitors on ADP- and thrombin-evoked Ca2+ fluxes were observed.
- Conventional PKC isoforms modulate platelet Ca2+ signalling in an agonist-dependent manner.
- PKC works to accelerate the activity of SERCA in response to both agonists.
- Thrombin-evoked Ca2+ signals are also modulated via an effect on the Na+/K+-ATPase.
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Authors
Robert A. Lever, Azhar Hussain, Benjamin B. Sun, Stewart O. Sage, Alan G.S. Harper,