Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10926217 | Cell Calcium | 2015 | 15 Pages |
Abstract
- Myenteric microvasculature developed synchronous spontaneous Ca2+ transients.
- Pericytes on precapillary arterioles and/or capillaries pace spontaneous Ca2+ transients in arterioles.
- Ca2+ transients in pericytes and smooth muscle cells arose through SR Ca2+ release.
- T-type Ca2+ channels were required for intercellular entrainment of Ca2+ transients.
- Interstitial cells and nerves had no role in microvasculature Ca2+ transients.
Keywords
α-SMAVDCCANO1FLCPDGFRαanoctamin-1PericyteTMEM16ASK3Platelet-derived growth factor receptor AICC-MYvWFsarco-endoplasmic reticulum calcium ATPaseICCPSSCPASMCBSACa2+ transientsT-type Ca2+ channelsbovine serum albumina-smooth muscle actinCyclopiazonic acidGastrointestinalphysiological saline solutionSmooth muscle cellFibroblast-like cellsinterstitial cells of CajalVon Willebrand factorSERCACapillariesVoltage-dependent Ca2+ channels
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Authors
Hikaru Hashitani, Retsu Mitsui, Shota Masaki, Dirk F. Van Helden,