| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10926218 | Cell Calcium | 2015 | 10 Pages |
Abstract
- Amphetamine (AMPH) and dopamine (DA) induce depolarizing currents through the DA transporter (DAT).
- DAT substrate-induced depolarization activates L-type but not N-type Ca2+ channels (CaV).
- AMPH is more potent than DA when activating L-type CaV.
- The activation of L-type CaV displays higher coupling-strength with AMPH- than DA-induced currents.
- AMPH action likely involves L-type CaV activation.
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Authors
Krasnodara N. Cameron, Ernesto Jr., Iwona Ruchala, Louis J. De Felice, Jose M. Eltit,