Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10926220 | Cell Calcium | 2015 | 13 Pages |
Abstract
- Downregulation of IP3R1 inhibits persistent Ca2+ oscillations in mouse eggs.
- Expression of wild type IP3R1 rescues ability to mount persistent Ca2+ oscillations.
- IP3R1s with phosphomimetic mutations show higher function and oscillations.
- Exogenous IP3R1s are resistant to downregulation, which enhance oscillations.
Keywords
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Authors
Nan Zhang, Sook Young Yoon, Jan B. Parys, Rafael. A. Fissore,