Article ID Journal Published Year Pages File Type
10926236 Cell Calcium 2015 15 Pages PDF
Abstract

- MDEB potentiates store-operated Ca2+ entry in various cancer cell lines.
- The action of MDEB is more specific than that of the generally used inhibitor 2-APB.
- MDEB has a strong stimulatory effect of PHA-mediated Ca2+ increase in Jurkat cells.
- MDEB increases apoptosis in fully activated Jurkat cells.
- MDEB may represent the first member of a new family of immunomodulators.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Authors
, , , , , , , , ,