Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10926236 | Cell Calcium | 2015 | 15 Pages |
Abstract
- MDEB potentiates store-operated Ca2+ entry in various cancer cell lines.
- The action of MDEB is more specific than that of the generally used inhibitor 2-APB.
- MDEB has a strong stimulatory effect of PHA-mediated Ca2+ increase in Jurkat cells.
- MDEB increases apoptosis in fully activated Jurkat cells.
- MDEB may represent the first member of a new family of immunomodulators.
Keywords
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Authors
Alaeddine Djillani, Isabelle Doignon, Tomas Luyten, Bouchaib Lamkhioued, Sophie C. Gangloff, Jan B. Parys, Oliver NüÃe, Christine Chomienne, Olivier Dellis,