Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10926237 | Cell Calcium | 2015 | 10 Pages |
Abstract
- Duchenne muscular dystrophy (DMD) is a progressive muscle disease with severe cardiac pathology.
- We show that mitochondrial function and structure progressively deteriorate in this disease.
- It is likely associated with excessive openings of mPTP due to oxidative stress and cellular Ca2+ overload.
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Authors
Victoria Kyrychenko, Eva Poláková, Radoslav JanÃÄek, Natalia Shirokova,