Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10926269 | Cell Calcium | 2014 | 11 Pages |
Abstract
- A hypotonic challenge activates a cation current carried by TRPV4 channels.
- TRPV4 currents can depolarize the cell.
- TRPV4 currents can explain hypotonicity-induced [Ca2+]i increase.
- TRPV4 channels are regulated by some obesity-altered agents.
- TRPV4 regulation may help to understand the link between OA and obesity.
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Authors
Julio C. Sánchez, Diego F. López-Zapata, Robert J. Wilkins,