| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10926298 | Cell Calcium | 2014 | 14 Pages |
Abstract
- Development of genetically encoded mitochondrial Ca2+-probe with high Kd (1.6 μM).
- Simultaneous TIRF images of mitochondrial and cytosolic Ca2+ fluxes in cardiomyocytes.
- Big mitochondrial Ca2+ signals accompany SR Ca2+ release and transmembrane Ca2+ influx.
- Cellular Ca2+ overload accentuates rapid mitochondrial Ca2+ uptake and release.
- Identified 2 Ca2+-signaling populations of mitochondria: peripheral and perinuclear.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Sarah Haviland, Lars Cleemann, Sarah Kettlewell, Godfrey L. Smith, Martin Morad,