| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10926365 | Cell Calcium | 2010 | 11 Pages |
Abstract
Using live imaging of the postsynaptic [Ca2+]i while monitoring the EPSP, we found that evoked transmitter release generates excitatory postsynaptic calcium concentration transients (EPSCaTs) by two mechanisms: (a) activation of DNQX-sensitive postsynaptic receptors-gated calcium influx and (b) calcium influx through nitrendipine-sensitive voltage-gated calcium channels (VGCCs). Concomitant confocal imaging of presynaptic boutons and EPSCaTs revealed that approximately 86% of the presynaptic boutons are associated with functional synapses.
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Authors
Guy Malkinson, Micha E. Spira,