| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10927021 | Cellular Immunology | 2012 | 11 Pages |
Abstract
- Human mesenchymal stem cells (MSCs) suppressed T cell proliferation and survival.
- The inhibitory effect of MSCs was mediated by CXCL3 and CXCR2 induction on T cells.
- This MSC-mediated T cells suppression influenced anti-tumor activity in vivo.
- Our study may provide useful information on MSC-mediated mechanism for tumor growth.
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Authors
Yong-Soo Lee, Kyung-Jong Won, Sung-Won Park, Hyeon-Woo Lee, Bokyung Kim, Jin-Hoi Kim, Dong-Ku Kim,