Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10927032 | Cellular Immunology | 2012 | 9 Pages |
Abstract
- Azithromycin, chloroquine and concanamycin impaire many lysosomal functions.
- Azithromycin and chloroquine deregulate TLR4 recycling, signaling and phospholipases.
- Stronger effect of concanamycin on lysosomes and TLR4 signaling.
- No effect of concanamycin on phospholipases and phospholipidosis.
- Impaired lysosomal functions - anti-inflammatory MOA of azithromycin and chloroquine.
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Authors
Krunoslav NujiÄ, Mihailo Banjanac, Vesna MuniÄ, Denis PolanÄec, Vesna ErakoviÄ Haber,