Article ID Journal Published Year Pages File Type
10927056 Cellular Immunology 2012 11 Pages PDF
Abstract
► Oral tolerance to OVA modifies the clinical course of CIA induced in BALB/c mice by administration of CII + OVA. ► Ingestion of OVA reduced serum levels of anti-CII antibodies and specific T cell proliferation. ► DCs from tolerant mice were able to suppress the immune responses of T lymphocytes from arthritic mice. ► Adoptive transfer of OVA-pulsed DCs mimic oral tolerance, suppressing the clinical signs of arthritis.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Authors
, , , , , ,