| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10929132 | Current Opinion in Cell Biology | 2012 | 8 Pages |
Abstract
⺠Human telomeres are protected from the DDR by a higher-order structure. ⺠Intermediate-state telomeres are susceptible to a DDR and regulate senescence. ⺠Uncapped-state telomeres are susceptible to fusions and induce crisis. ⺠Intermediate-state telomeres regulate the prolonged mitosis checkpoint. ⺠Telomeres may serve as epigenetic sensors of cellular stress.
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Authors
Anthony J Cesare, Jan Karlseder,