| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10929151 | Current Opinion in Cell Biology | 2012 | 5 Pages |
Abstract
The cytoprotective properties of vertebrate inhibitor of apoptosis (IAP) proteins have been the subject of much study. These proteins have, however, emerged as key signaling intermediates modulating a variety of cellular functions through their ability to act as E3 ubiquitin ligases. This review will focus on the cell death-independent roles of the IAP proteins, focusing on recent reports indicating that c-IAPs and XIAP are key molecules involved in modulating cell migration and development.
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Authors
Niall S Kenneth, Colin S Duckett,