Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10929206 | Current Opinion in Cell Biology | 2011 | 8 Pages |
Abstract
⺠Ca2+ and PKA are pleiotropic cellular regulators of cell migration. ⺠There are numerous mechanisms through which Ca2+ and PKA can regulate each other. ⺠TRP channels and store-operated Ca2+ entry are newly and strongly implicated in migration. ⺠We present published and new, unpublished data connecting PKA to TRP channels and SOCE. ⺠We hypothesize that Ca2+/PKA cross-talk is an important regulatory axis for migration.
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Authors
Alan K Howe,