| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10929211 | Current Opinion in Cell Biology | 2011 | 10 Pages |
Abstract
⺠Invadosome assembly is promoted by extracellular matrix signaling. ⺠Invadosomes sense the mechano-chemical properties of extracellular matrix. ⺠β1/β3 integrins cross-talk in invadosome is revealed by their spatial organization. ⺠Reinforcement of Src signaling by PKC stimulates invadosome assembly. ⺠Invadosomes facilitate invasion through 3D actinic architecture coupled with intense protein trafficking.
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Authors
Olivier Destaing, Marc R Block, Emmanuelle Planus, Corinne Albiges-Rizo,