| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10929212 | Current Opinion in Cell Biology | 2011 | 8 Pages |
Abstract
⺠Integrin activation mechanisms differ between individual integrins. ⺠Integrin activation mechanisms differ for non-adherent and adherent cells. ⺠Integrins in adherent cells are strongly regulated by trafficking mechanisms. ⺠It is unclear how the NxxY motifs in the β-cytoplasmic tails regulate integrin trafficking. ⺠The α-subunits are important regulators of integrin trafficking.
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Authors
Coert Margadant, Hanneke N Monsuur, Jim C Norman, Arnoud Sonnenberg,