Article ID Journal Published Year Pages File Type
10929215 Current Opinion in Cell Biology 2011 8 Pages PDF
Abstract
► αvβ3-Integrin antagonists function differently depending on the matrix to which cells are bound. ► The achieved dose of αvβ3-integrin antagonist dictates the angiogenic response. ► Cell-type-specific expression of αvβ3-integrin determines its role in tumor angiogenesis. ► αvβ3-integrin interacts with a large array of other proteins and these interactions may vary its angiogenic function.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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