Article ID Journal Published Year Pages File Type
10929216 Current Opinion in Cell Biology 2011 9 Pages PDF
Abstract
► Tube formation requires coordinated polarized vesicle trafficking and cell division. ► The core-machinery for membrane lumen initiation is conserved from yeast to humans. ► Phosphoinositides and small GTPases regulate membrane trafficking during morphogenesis. ► Microtubule- and actin-binding proteins, and motors aid vesicle transport to the lumen. ► Cdc42 and the Par complex integrate cell division with polarity to form the lumen.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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