| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10929257 | Current Opinion in Cell Biology | 2013 | 8 Pages |
Abstract
The importance of cell migration for both normal physiological functions and disease processes has been clear for the past 50 years. Although investigations of two-dimensional (2D) migration in regular tissue culture have elucidated many important molecular mechanisms, recent evidence suggests that cell migration depends profoundly on the dimensionality of the extracellular matrix (ECM). Here we review a number of evolving concepts revealed when cell migration is examined in different dimensions.
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Authors
Andrew D Doyle, Ryan J Petrie, Matthew L Kutys, Kenneth M Yamada,