Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10929535 | Current Opinion in Cell Biology | 2005 | 7 Pages |
Abstract
Metazoan replication-dependent histone mRNAs are the only eukaryotic mRNAs that lack polyA tails. The genes for the five histone proteins have remained physically linked during evolution. Expression of histone mRNAs and histone proteins requires a unique set of factors, and may be coordinated by association of the histone genes with Cajal bodies. Recently several novel factors, including components of the U7 snRNP, as well as proteins involved in regulation of histone gene expression, have been described.
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Authors
William F Marzluff,