| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10930335 | Cytotherapy | 2016 | 10 Pages |
Abstract
hADSC CM neither induced an enrichment of CSCs in U87 cells population nor interfered in the response to TMZ in culture. Nevertheless, paracrine factors released by hADSCs were able to modulate glioblastoma cells migration. These findings provide novel information regarding the safety of using hADSCs against cancer and highlight the importance of considering hADSC-tumor cells interactions in tumor microenvironment in the design of novel cell therapies.
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Authors
Giovana Ravizzoni Onzi, PÃtia Flores Ledur, Luana Dimer Hainzenreder, Ana Paula Santin Bertoni, Andrew Oliveira Silva, Guido Lenz, Márcia Rosângela Wink,