| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10930354 | Cytotherapy | 2016 | 10 Pages |
Abstract
Human adult PB and UCB-derived T cells expressing a CAR derived from the TCR-like 8F4 antibody rapidly and efficiently kill AML in vitro. Our data could lead to a new treatment paradigm for AML in which targeting leukemia stem cells could transfer long-term immunity to protect against relapse.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Qing Ma, Haven R. Garber, Sijie Lu, Hong He, Eran Tallis, Xiaoling Ding, Anna Sergeeva, Michael S. Wood, Gianpietro Dotti, Barbara Salvado, Kathryn Ruisaard, Karen Clise-Dwyer, Lisa St John, Katayoun Rezvani, Gheath Alatrash, Elizabeth J. Shpall,