Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10930509 | Cytotherapy | 2015 | 17 Pages |
Abstract
We have produced a simple, inexpensive and easily adoptable protocol for the generation of CAR19 T cells suitable for use in clinical trials using the piggyBac transposon system. This provides a robust platform for further enhancing the T-cell product and testing new CAR technologies.
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Authors
Saumya Ramanayake, Ian Bilmon, David Bishop, Ming-Celine Dubosq, Emily Blyth, Leighton Clancy, David Gottlieb, Kenneth Micklethwaite,