Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10930592 | Cytotherapy | 2012 | 11 Pages |
Abstract
The feedback loop between MSC or Fb and activated T cells may limit the immunosuppressive effects of MSC and Fb to sites containing ongoing immunologic or inflammatory responses where activated T cells induce the up-regulation of IDO and immunomodulatory properties of MSC and Fb. These data demonstrate that hESC-MSC may be evaluated further as an allogeneic cell source for therapeutic applications requiring immunosuppression.
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Authors
Wenyu Lin, Steve K.W. Oh, Andre B.H. Choo, Andrew J.T. George,