| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10930592 | Cytotherapy | 2012 | 11 Pages |
Abstract
The feedback loop between MSC or Fb and activated T cells may limit the immunosuppressive effects of MSC and Fb to sites containing ongoing immunologic or inflammatory responses where activated T cells induce the up-regulation of IDO and immunomodulatory properties of MSC and Fb. These data demonstrate that hESC-MSC may be evaluated further as an allogeneic cell source for therapeutic applications requiring immunosuppression.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Wenyu Lin, Steve K.W. Oh, Andre B.H. Choo, Andrew J.T. George,