Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10930655 | Cytotherapy | 2013 | 10 Pages |
Abstract
These results demonstrate that bovine oocyte extract reactivates epigenetically silenced tumor suppressor genes by remodeling the epigenetic modifications at their promoter regions. Bovine oocyte extract may provide a useful tool for investigating epigenetic mechanisms in cancer and a valuable source for developing novel safe therapeutic approaches that target epigenetic alterations.
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Authors
Zhenfei Wang, Yongli Yue, Pengyong Han, Rula Sa, Xiaolv Ren, Jie Wang, Haidong Bai, Haiquan Yu,