Article ID Journal Published Year Pages File Type
10932162 Developmental Biology 2013 16 Pages PDF
Abstract
► The TGFβ ligands Actβ, Daw, Mav and Myo are required in the wing disc for growth. ► The receptor Babo and Smad2 regulate cell size and the length of the cell cycle. ► Activation of Babo and phosphorylation of Smad2 is generalised in the wing disc. ► Over-expression of activated Babo reduces the levels of phosphorylated Mad. ► Over-expression of activated Babo activates Mad in the absence of Smad2.
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