Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932162 | Developmental Biology | 2013 | 16 Pages |
Abstract
⺠The TGFβ ligands Actβ, Daw, Mav and Myo are required in the wing disc for growth. ⺠The receptor Babo and Smad2 regulate cell size and the length of the cell cycle. ⺠Activation of Babo and phosphorylation of Smad2 is generalised in the wing disc. ⺠Over-expression of activated Babo reduces the levels of phosphorylated Mad. ⺠Over-expression of activated Babo activates Mad in the absence of Smad2.
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Authors
Covadonga F. Hevia, Jose F. de Celis,