Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932165 | Developmental Biology | 2013 | 11 Pages |
Abstract
⺠The function of Integrin signaling in fly intestinal stem cells was investigated. ⺠αPS1 (mew),αPS3(scb) and βPS (mys) are expressed in ISCs for maintenance. ⺠Integrin signaling is required for ISC proliferation but not survival. ⺠Disruption of integrin triggers cell cycle arrest and prevents tumorigenesis.
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Authors
Guonan Lin, Xi Zhang, Juan Ren, Zhimin Pang, Chenhui Wang, Na Xu, Rongwen Xi,