Article ID Journal Published Year Pages File Type
10932165 Developmental Biology 2013 11 Pages PDF
Abstract
► The function of Integrin signaling in fly intestinal stem cells was investigated. ► αPS1 (mew),αPS3(scb) and βPS (mys) are expressed in ISCs for maintenance. ► Integrin signaling is required for ISC proliferation but not survival. ► Disruption of integrin triggers cell cycle arrest and prevents tumorigenesis.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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Integrin signaling is required for maintenance and proliferation of intestinal stem cells in Drosophila
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