Article ID Journal Published Year Pages File Type
10932187 Developmental Biology 2013 13 Pages PDF
Abstract
► The zebrafish ventral to dorsal BMP activity gradient is established by 40% epiboly. ► Graded expression of BMP ligands precedes the formation of the activity gradient. ► There is no evidence that BMP2B protein diffuses to form the BMP activity gradient. ► The BMP activity gradient is determined by graded ligand expression. ► Graded bmp2b transcription is due to temporal regulation by Dharma, FGF, and Chordin.
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