| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10932191 | Developmental Biology | 2012 | 12 Pages |
Abstract
⺠E-cadherin loss in the developing intestinal epithelium caused neonatal lethality. ⺠Intestinal epithelial architecture was severely disrupted in E-cadherin mutants. ⺠Barrier function was compromised in E-cadherin mutants. ⺠Mutant intestine contained more proliferating cells but fewer enterocytes. ⺠β-catenin target gene expression was increased, but β-catenin was less abundant in mutants.
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Authors
Benjamin J. Bondow, Mary L. Faber, Kevin J. Wojta, Emily M. Walker, Michele A. Battle,