| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10932215 | Developmental Biology | 2013 | 10 Pages |
Abstract
⺠Hair shaft defects result from ectodermal activation of Kras in mice. ⺠Shh is a RAS-responsive target gene. ⺠Shh levels acutely respond to FGF stimulation or MAPK/PI3K inhibition. ⺠Shh RNA has a short half-life and its levels are dependent on transcription. ⺠Ectodermal Fgfr2 regulates Shh levels in vivo.
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Authors
Anandaroop PhD, Suguna Rani PhD, Christopher Cowing-Zitron, Nai-Jung PhD, Heather Reilly-Rhoten, Julianne Burns, Benjamin D. MD, PhD,