Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932237 | Developmental Biology | 2012 | 11 Pages |
Abstract
⺠Expression of bcl2l in the thyroid primordium is necessary against cell death. ⺠Thyroid transcription factors inhibit cell death by regulating bcl2l expression. ⺠This mechanism removes cells that do not express the complement of thyroid transcription factors. ⺠This is the first description of an active mechanism to protect the thyroid during morphogenesis.
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Authors
Immacolata Porreca, Elena De Felice, Henrik Fagman, Roberto Di Lauro, Paolo Sordino,