Article ID Journal Published Year Pages File Type
10932237 Developmental Biology 2012 11 Pages PDF
Abstract
► Expression of bcl2l in the thyroid primordium is necessary against cell death. ► Thyroid transcription factors inhibit cell death by regulating bcl2l expression. ► This mechanism removes cells that do not express the complement of thyroid transcription factors. ► This is the first description of an active mechanism to protect the thyroid during morphogenesis.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Authors
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