A network of PUF proteins and Ras signaling promote mRNA repression and oogenesis in C. elegans

Article ID	Journal	Published Year	Pages	File Type
10932247	Developmental Biology	2012	14 Pages	PDF

Abstract

âº Two PUF RNA-binding protein groups control different processes in oogenesis. âº PUF-3/11 and PUF-5/6/7 repress translation of distinct and common mRNAs. âº Ras-MapKinase pathway promotes translational repression by PUF-5/6/7. âº Ras-MapKinase regulates PUF-5 protein. âº Ras-MapKinase and PUF-5/6/7 cooperate to control oocyte organization.

Keywords

ERK RAS Oogenesis Translation RNA-binding protein Translational control MAP kinase

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology

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A network of PUF proteins and Ras signaling promote mRNA repression and oogenesis in C. elegans

Authors

Arnaud Hubstenberger, Cristiana Cameron, Rebecca Shtofman, Shiri Gutman, Thomas C. Evans,