| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10932262 | Developmental Biology | 2012 | 10 Pages |
Abstract
⺠The long non-coding RNA, MHM, is localised in the nucleus of female chick embryos. ⺠The antisense MHM strand is also expressed, and has a cytoplasmic localisation. ⺠Over-expression of MHM causes developmental abnormalities in chicken embryos. ⺠MHM over-expression disrupts expression of the testis-determining gene, DMRT1. ⺠MHM over-expression induces bilateral ovarian development in females.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Kelly N. Roeszler, Catherine Itman, Andrew H. Sinclair, Craig A. Smith,