| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10932263 | Developmental Biology | 2012 | 14 Pages |
Abstract
⺠TCF responsive elements linked to a fluorescent reporter reveal Wnt/b-catenin activity in a whole zebrafish. ⺠Wnt reporter (7xTCFsiam) fish unveils novel tissues of wnt/b-catenin dynamic expression. ⺠Wnt activity can be followed in vivo in embryonic, larval and adult sensory organs and brain endothelia. ⺠Wnt signaling is revealed in vivo in regenerating tissues. ⺠Wnt reporter fish can be used both for drug screenings and wnt mutants phenotyping.
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Authors
Enrico Moro, Gunes Ozhan-Kizil, Alessandro Mongera, Dimitris Beis, Claudia Wierzbicki, Rodrigo M. Young, Despina Bournele, Alice Domenichini, Leonardo E. Valdivia, Lawrence Lum, Chuo Chen, James F. Amatruda, Natascia Tiso, Gilbert Weidinger,