Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932273 | Developmental Biology | 2012 | 11 Pages |
Abstract
⺠We identify regulatory elements to control Six6 expression in the ventral forebrain and eye. ⺠The forebrain Six6 enhancer is dependent on homeodomain and SoxB1 binding sites. ⺠SoxB1 binds and activates the Six6 forebrain enhancer. ⺠SoxB1 mutants fail to activate Six6 transcription in the ventral forebrain.
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Authors
Bumwhee Lee, Karine Rizzoti, David S. Kwon, Seon-Young Kim, Sangtaek Oh, Douglas J. Epstein, Youngsook Son, Jaeseung Yoon, Kwanghee Baek, Yongsu Jeong,