Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932294 | Developmental Biology | 2012 | 12 Pages |
Abstract
⺠Agr2, previously implicated in breast cancer, regulates mammary gland development. ⺠Estrogen-induced Agr2 expression is developmentally regulated in mammary gland. ⺠Over-expression induces epithelial cell proliferation in virgin mammary glands. ⺠Over-expression induces precocious lobuloalveolar development in virgin mice. ⺠Agr2 deletion impairs cell proliferation and alveologenesis during pregnancy.
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Authors
Suman Verma, Michael L. Salmans, Mikhail Geyfman, Hong Wang, Zhengquan Yu, Zhongxian Lu, Fang Zhao, Steven M. Lipkin, Bogi Andersen,