Article ID Journal Published Year Pages File Type
10932294 Developmental Biology 2012 12 Pages PDF
Abstract
► Agr2, previously implicated in breast cancer, regulates mammary gland development. ► Estrogen-induced Agr2 expression is developmentally regulated in mammary gland. ► Over-expression induces epithelial cell proliferation in virgin mammary glands. ► Over-expression induces precocious lobuloalveolar development in virgin mice. ► Agr2 deletion impairs cell proliferation and alveologenesis during pregnancy.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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