Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932306 | Developmental Biology | 2012 | 11 Pages |
Abstract
⺠Ndrg2 is expressed in the PSM and mesenchyme of developing somites. ⺠Loss of Ndrg2 in mice resulted in vertebral homeotic transformations. ⺠Loss of Ndrg2 in osteoblasts or chondrocytes resembles the vertebral defects in Ndrg2â/â mice. ⺠Ndrg2 instructs vertebral specification via the Hox genes and Bmp signaling.
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Authors
Huang Zhu, Jianzhi Zhao, Wenrong Zhou, Hanjun Li, Rujiang Zhou, Lingling Zhang, Haixia Zhao, Jingjing Cao, Xuming Zhu, Hongliang Hu, Gang Ma, Lin He, Zhengju Yao, Libo Yao, Xizhi Guo,