Article ID Journal Published Year Pages File Type
10932306 Developmental Biology 2012 11 Pages PDF
Abstract
► Ndrg2 is expressed in the PSM and mesenchyme of developing somites. ► Loss of Ndrg2 in mice resulted in vertebral homeotic transformations. ► Loss of Ndrg2 in osteoblasts or chondrocytes resembles the vertebral defects in Ndrg2−/− mice. ► Ndrg2 instructs vertebral specification via the Hox genes and Bmp signaling.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Authors
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