Article ID Journal Published Year Pages File Type
10932312 Developmental Biology 2012 7 Pages PDF
Abstract
► Deletion of Sin3A in the germ cell lineage leads to male sterility. ► Sin3A-deleted testes acquire a Sertoli cell only phenotype. ► Sin3A prevents apoptosis in male germ cells resuming mitosis at birth. ► Germ cell loss triggered by Sin3A deletion affects the Sertoli cells expression program.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Authors
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