Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932320 | Developmental Biology | 2012 | 13 Pages |
Abstract
⺠We resolved the boundaries of mouse hemangioblast maturation at headfold stages. ⺠HoxB4 and GATA1 are the first markers that distinguish vessel and blood lineages. ⺠A third population co-expresses both markers, indicating a metastable state. ⺠We found similar states in rare cells at earliest sites of HSC emergence. ⺠We formalized our observations using a heuristic Netlogo model.
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Authors
Jerry M. Rhee, Philip M. Iannaccone,