Article ID Journal Published Year Pages File Type
10932320 Developmental Biology 2012 13 Pages PDF
Abstract
► We resolved the boundaries of mouse hemangioblast maturation at headfold stages. ► HoxB4 and GATA1 are the first markers that distinguish vessel and blood lineages. ► A third population co-expresses both markers, indicating a metastable state. ► We found similar states in rare cells at earliest sites of HSC emergence. ► We formalized our observations using a heuristic Netlogo model.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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