| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10932325 | Developmental Biology | 2012 | 10 Pages |
Abstract
⺠Irf6 mutants show evagination of incisor tooth epithelium, rather than invagination. ⺠Evagination in Irf6 mutants phenocopies those seen in Ikkα mutants. ⺠No genetic interaction between Irf6 and Ikka in epithelial invagination. ⺠The Wnt pathway is normally suppressed by Ikkα/Irf6 in epithelial invagination. ⺠Ikkα/Irf6 regulates epithelial invagination via NF-κB-independent pathway.
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Authors
James Blackburn, Atsushi Ohazama, Katsushige Kawasaki, Yoko Otsuka-Tanaka, Bigang Liu, Kenya Honda, Ryan B. Rountree, Yinling Hu, Maiko Kawasaki, Walter Birchmeier, Ruth Schmidt-Ullrich, Akira Kinoshita, Brian C. Schutte, Nigel L. Hammond,