Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932336 | Developmental Biology | 2012 | 12 Pages |
Abstract
⺠Hmx1 is a transcription factor linked to ear malformations in humans, rats, and mice. ⺠Hmx1 is expressed in somatosensory neurons, including all sensory modalities. ⺠The mouse “Dumbo” (dm) mutation is a complete loss of function for Hmx1. ⺠DRG neurons in Hmx1dm/dm embryos undergo neurogenesis normally. ⺠Hmx1dm/dm embryos have defects in the geniculate ganglion/posterior auricular nerve.
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Authors
Lely A. Quina, Lynne Tempest, Yun-Wei A. Hsu, Timothy C. Cox, Eric E. Turner,