Article ID Journal Published Year Pages File Type
10932339 Developmental Biology 2012 14 Pages PDF
Abstract
► Arx is expressed in GI endocrine progenitors and in hormone producing cells. ► Ablation of Arx in mice results in changes in enteroendocrine subtypes. ► Arx acts as a cell fate determinant in endocrine progenitors. ► Ileal lipid droplet accumulation observed in the Arx-deficient mice. ► Human intestinal endocrine cell development requires ARX.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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