Article ID Journal Published Year Pages File Type
10932347 Developmental Biology 2012 12 Pages PDF
Abstract
► Retinoic acid signaling is required for upper lip and primary palate formation. ► Retinoic acid signaling regulates expression of homeobox genes msx2 and lhx8. ► Retinoic acid signaling and Msx2/Lhx8 regulate cell proliferation and differentiation. ► Median facial clefts form in embryos deficient in retinoic acid, Lhx8 and Msx2.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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Median facial clefts in Xenopus laevis: Roles of retinoic acid signaling and homeobox genes
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